Our first publication for 2021 is on-line
01/20/2021We are very happy to share here that our research article at Angew. Chem. Int. Ed., entitled "Highly Enantioselective Cobalt‐Catalyzed (3 + 2) Cycloadditions of Alkynylidenecyclopropanes" and authored by E. Da Concepción, I. Fernández, J. L. Mascarenas and F. López, has been accepted and it's already available through the journal website.
Abstract: Low‐valent cobalt complexes equipped with chiral ligands can efficiently promote highly enantioselective (3+2) cycloadditions of alkyne‐tethered alkylidenecyclopropanes. The annulation allows to assemble bicyclic systems containing five‐membered rings in good yields and with excellent enantiomeric ratios. We also present a mechanistic discussion based on experimental and computational data, which support the involvement of Co(I)/Co(III) catalytic cycles
External link: https://onlinelibrary.wiley.com/doi/10.1002/anie.202015202