Our first ChemistryEurope (European Chemical Societies Publishing) article is already available on-line
03/25/2025We are so happy to announce here that our recent research article at Chemistry Europe, entitled "Palladium-Catalyzed [3+2] Cycloadditions of Alkylidenecyclopropanes to Imines: A Direct Approach to Pyrrolidine Scaffolds" and authored by R. Rodiño, F.
Verdugo, J. L. Mascareñas and F. López, has been accepted and it's already on-line (gold Open Access).
Abstract: Pd-catalyzed annulations of ACPs with different C=N partners in both inter- and intramolecular ways are described. The methods provide access to pyrrolidines and pyrrolidine-fused polycyclic systems, featuring β-exo-methylene moieties. Preliminary enantioselective variant has been shown by using a chiral phosphoramidite ligand and DFT studies shed light on the reaction mechanism
External link: https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ceur.202500005