Just accepted our last paper in Angew. Chem. Int. Ed.


"Rhodium(III)‐Catalyzed Annulation of 2‐Alkenylanilides with Alkynes via C‐H Activation: a Direct Access to 2‐substituted Indolines" by Font, M., Cendón, B., Seoane, A., Mascareñas, J.L., and Gulías, M., is our recent communication to Angewandte Chemie International Edition

A Rh(III) complex featuring an electron‐deficient η5‐cyclopentadienyl ligand catalyzes an unusual annulation between alkynes and 2‐alkenylanilides, to form synthetically appealing 2‐substituted indolines. Formally, the process can be viewed as an allylic amination with concomitant hydrocarbonation of the alkyne. Mechanistic experiments indicate that this transformation involves a peculiar Rhodium migration with a concomitant 1,5‐H shift.

External link: https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201802830