We are really pleased to announce the accepted paper at Chem. Sci. is already available
Our latest paper at the Chemical Science journal, entitled "Hollow Nanoreactors for Pd-catalyzed Suzuki- Miyaura Couplings and O-Propargyl Cleavage Reactions in Bio-relevant Aqueous Media ", by P. Destito, A. Sousa-Castillo, J. R. Couceiro, F. López, M. Angel Correa-Duarte and J. L. Mascareñas has been published.
We describe the fabrication of hollow microspheres consisting of mesoporous silica nanoshells decorated with an inner layer of palladium nanoparticles, and their use as Pd-nanoreactors in aqueous media. These palladium-equipped capsules can be used to promote the uncaging of propargyl-protected phenols, as well as Suzuki-Miyaura cross-couplings, in water, and under physiologically compatible temperatures. Importantly, the depropargylation reaction can be accomplished in a bioorthogonal manner in presence of relatively high concentrations of biomolecular components, and even in the presence of mammalian cells.
External link: https://pubs.rsc.org/en/Content/ArticleLanding/2019/SC/C8SC04390F#!divAbstract